Basis, indications and risk: Pharmacological therapy
Non-steroid antiinflammatory drugs (NSAIDS)
Objective
To decrease the inflammation complicating most
back pain.
Theoretical basis
The onset of inflammation
is due to the release of different molecules. Non-steroid antiinflammatory
drugs basically act by hindering the production or release of these
molecules.
Evidence of efficacy
There are many studies proving the effectiveness of non-steroid
antiinflammatory drugs to reduce pain and mobility limitations present
in acute episodes of back pain. The existing evidence-based recommendations
establish that, although frequently prescribed along with muscle
relaxants, this combination has not proven to produce a better effect
than each component on its own.
The existing evidence-based recommendations
recognize the efficacy of antiinflammatory drugs to improve back
pain and state that the different types of these drugs have a very
similar rate of effectiveness. The recommendations also note that
these drugs are more effective in treating back pain than radiated
pain.
Risks and side effects
When taking a non-steroid antiinflammatory drug orally, by suppository,
or by intramuscular injection, the medication is introduced into
the blood and is distributed throughout the body. The portion that
finally reaches the structures involved in back pain may cause improvement,
but the remaining portion that has reached other parts of the body
is useless and may produce adverse effects.
Adverse reactions are specific to each type of
drug and are detailed in the package inserts of the pharmaceutical
product. The most frequent adverse effects are digestive tract disorders
which range from heartburn to bleeding ulcers and, less frequently,
kidney damage.
The longer a pharmacological drug is used, the
less its rate of effectiveness and the greater the risk of side
effects. Therefore it is important to follow your physician's recommendations
precisely.
Do not use drugs that have previously caused allergies,
nor those not prescribed by your physician.
Recommendations
The use of anti-inflammatory drugs is recommended
to ease the intensity of symptoms during the periods of acute pain
or during crises or chronic pain exacerbation. They are the most
widely used pharmaceuticals in these cases.
In general, with exceptions, they should not be
used during more than 14 consecutive days to avoid risk of adverse
effects.
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