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Working methods

Electronic search strategies

The most sensitive (exhaustive) strategy is used for studies published from 1997 onwards. A more specific (restrictive) strategy is used for studies published previously.

The strategy used for the years from 1997 onward for the MEDLINE, Health Star, Psychoinfo and Bioethics databases is:

  1. explode "Low-Back-Pain"/ all subheadings
  2. explode "Sciatica"/ all subheadings
  3. explode "Intervertebral-Disk-Displacement"/ all subheadings
  4. explode "Intervertebral-Disk-Chemolysis"/ all subheadings
  5. explode "Back-Pain"/ all subheadings
  6. #1 or #2 or #3 or #4 or #5
  7. (letter or editorial or case-report or historical-article or historical-biography or comment or interview) in pt
  8. #6 not #7
  9. (english or spanish or french or german) in la
  10. #8 and #9
  11. low back pain
  12. sciatica
  13. intervertebral disk displacement
  14. intervertebral disk chemolysis
  15. back pain
  16. #11 or #12 or #13 or #14 or #15
  17. #16 or #10
  18. #17 and (human in tg)

The strategy used for the years 1997 and thereafter for the EMBASE databases is:

  1. BACKACHE#
  2. low-back-pain
  3. ischialgia. DE, AB, TI.
  4. sciatica. AB, TI.
  5. intervertebral-disk-hernia#
  6. chemonucleolysis. DE, AB, TI.
  7. backache. AB, TI.
  8. low ADJ back ADJ pain. AB, TI.
  9. intervertebral ADJ disk ADJ displacement$1. AB, TI.
  10. 1 OR 2 OR 3 OR 4 OR 5 OR 6 OR 7 OR 8 OR 9
  11. letter#
  12. editorial#
  13. case-report#
  14. history-of-medicine#
  15. comments$1. TI.
  16. interviews$1. DE, AB, TI.
  17. 11 OR 12 OR 13 OR 14 OR 15 OR 16
  18. 10 NOT 17
  19. 18 H = Y
  20. 19 AND (en. LG. OR fr. LG. OR sp. LG. OR ge. LG.)
  21. 20 AND abstract. AB.
  22. 21 YR > 96

The strategy used for 1996 previous years for the MEDLINE, Health Star, Psychoinfo and Bioethics databases is:

  1. Case-Control-Studies"
  2. "Cohort-Studies"
  3. #1 or #2
  4. explode "Sensitivity-and-Specificity"/ all subheadings
  5. predictive
  6. value*
  7. (predictive and value*) in ti,ab,mesh
  8. #4 or #7
  9. prognosis
  10. prognosis in mesh
  11. explode "Survival-Analysis"/ all subheadings
  12. #10 or #11
  13. meta?anal*
  14. meta
  15. anal*
  16. (meta?anal* or meta anal*) in ti,ab
  17. quantitativ*
  18. review*
  19. quantitativ*
  20. overview*
  21. (quantitativ* review* or quantitativ* overview*) in ti,ab
  22. systematic*
  23. review*
  24. systematic*
  25. overview*
  26. (systematic* review* or systematic* overview*) in ti,ab
  27. methodologic*
  28. review*
  29. methodologic*
  30. overview*
  31. (methodologic* review* or methodologic* overview*) in ti,ab
  32. integrative
  33. research
  34. review*
  35. research
  36. integration*
  37. (integrative research review* or research integration*) in ti,ab
  38. review
  39. review in pt,mesh
  40. review*
  41. review* in ti,ab
  42. overview*
  43. overview* in ti,ab
  44. quantitativ*
  45. synthes*
  46. quantitativ* synthes* in ti,ab
  47. meta-analysis
  48. meta-analysis in pt,mesh
  49. #48 or #16 or #21 or #26 or #31 or #37 or #46
  50. #49 and (#39 or #41 or #43)
  51. double
  52. blind*
  53. (double and blind*) in ti,ab,mesh
  54. placebo*
  55. placebo* in ti,ab,mesh
  56. #53 or #55
  57. #3 or #8 or #12 or #50 or #56
  58. explode "Low-Back-Pain"/ all subheadings
  59. explode "Sciatica"/ all subheadings
  60. explode "Intervertebral-Disk-Displacement"/ all subheadings
  61. explode "Intervertebral-Disk-Chemolysis"/ all subheadings
  62. explode "Back-Pain"/ all subheadings
  63. #58 or #59 or #60 or #61 or #62
  64. (letter or editorial or case-report or historical-article or historical-biography or comment or interview) in pt
  65. #63 not #64
  66. (english or spanish or french or german) in la
  67. #65 and #66
  68. low back pain
  69. sciatica
  70. intervertebral disk displacement
  71. intervertebral disk chemolysis
  72. back pain
  73. #68 or #69 or #70 or #71 or #72
  74. #73 or #67
  75. #57 and #74

The strategy used for 1996 and previous years for the EMBASE database is:

  1. BACKACHE#
  2. low-back-pain
  3. ischialgia. DE, AB, TI.
  4. sciatica. AB, TI.
  5. intervertebral-disk-hernia#
  6. chemonucleolysis. DE, AB, TI.
  7. backache. AB, TI.
  8. low ADJ back ADJ pain. AB, TI.
  9. intervertebral ADJ disk ADJ displacement$1. AB, TI.
  10. 1 OR 2 OR 3 OR 4 OR 5 OR 6 OR 7 OR 8 OR 9
  11. letter#
  12. editorial#
  13. case-report#
  14. history-of-medicine#
  15. comments$1. TI.
  16. interviews$1. DE, AB, TI.
  17. 11 OR 12 OR 13 OR 14 OR 15 OR 16
  18. 10 NOT 17
  19. 18 H = Y
  20. 19 AND (en. LG. OR fr. LG. OR sp. LG. OR ge. LG.)
  21. 20 AND abstract. AB.
  22. 21 YR > 89
  23. 22 YR <97
  24. (Case ADJ Control ADJ Study OR (Case ADJ Control ADJ Study OR (Case ADJ Control ADJ Study OR (Case ADJ Control ADJ Study OR Case-Control-Study)))). DE, AB, TI. OR (Cohort ADJ Analysis OR (Cohort ADJ Analysis OR (Cohort ADJ Analysis OR (Cohort ADJ Analysis OR Cohort-Analysis)))). DE, AB, TI.
  25. Survival#. DE.
  26. Epidemiology#. DE.
  27. prognosis. DE.
  28. placebo$. DE, AB, TI.
  29. double. DE, AB, TI. AND blind$. DE, AB, TI.
  30. Predictive. DE, AB, TI. AND value$. DE, AB, TI.
  31. 24 OR 25 OR 26 OR 27 OR 28 OR 29 OR 30
  32. 23 AND 31

The strategy used for the Pascal database is:

  1. Clinical trial* or randomi* control* trial* or drug* therap* or therapeutic* use or random* or double* or blind or placebo* or random* allocation* or single blind method*
  2. cohort* stud* or incidence* or mortality or follow* up stud* or prognos* or survival analysis* or predictiv* or epidemiolog*
  3. sensitivit* or specificit* or diagnos* or predictiv* value or risk* or odd or ratio* or relativ* or case* control*
  4. meta*analys* or meta-analys* or review* or quantitativ* or systematic* or methodolog* or overview* or integrativ* research*
  5. letter or editorial or case report or historical article or historical biography or comment or interview
  6. english or spanish or french or german
  7. low back pain or sciatica or intervertebral dis* displacement or intervertebral dis* chemolysis or back pain
  8. #1 or #2 or #3 or #4
  9. (#8 not #5) and #6 and #7

Quality Control Procedures:

The outcome of the automatic search is systematically compared with the results of a manual search, considered as the gold standard. Manual searching includes the 10 journals with the greatest number of articles published on common back pain from 1989 through 1999, along with an additional list of 20 other journals, selected by the Editorial Committee in relation to their specialty and impact. The purpose is to detect if automatic searching has missed any of the articles gathered manually. Should this occur would be developed and implemented a more sensitive electronic search strategy.

The 10 journals that have published the greatest number of articles on common back pain from 1989 through to 1999 are:

  • Spine
  • Journal of Manipulative Physiotherapy
  • Journal of Spinal Disorders
  • European Spine Journal
  • Journal of Neurosurgery
  • Archives of Physical Medicine Rehabilitation
  • Physical Therapy
  • BMJ (British Medical Journal)
  • Revue du Rhumatisme, english edition
  • Pain

The 20 journals selected by the Editorial Committee are:

  • New England Journal of Medicine
  • Lancet
  • Annals of Internal Medicine
  • JAMA (Journal of the American Medical Association)
  • Journal of Investigative Medicine
  • British Medical Journal
  • Archives of Internal Medicine
  • Medicine
  • Annual Review of Medicine
  • American Journal of Medicine
  • Journal of Internal Medicine
  • British Journal of General Practice
  • Mayo Clinic Proceedings
  • European Journal of Clinical Investigation
  • Journal of Pain Symptom Management
  • British Medical Bulletin
  • Quarterly Journal of Medicine
  • Advances in Internal Medicine
  • Medicina Clínica
  • Canadian Medical Association Journal


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